In the worrying tendency of colorectal cancer cases among young people, a new study has identified a possible source.
Researchers from the University of California San Diego have added a bacterial poison called Calibactein to the growth of the initial start.
Researchers say that some of the strains of Coalibactin Escrechia Colli (E. Coli) are produced by the colon and the anus.
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The exposure of bacteria toxin during childhood can change the DNA of colon cells in a way that increases the risk of colorectal cancer before the age of 50, survey.
In the study, researchers have analyzed 981 colorectal cancer genome to patients with primary-looking and late-source colorectal cancer patients across 11 countries. (Estock)
This research, which is meaningful by the Cancer Research UK, was published in the journal April 23.
Fox told Digital, “The key acceptance is that the contact of Collibutin is probably a major contributor to the early colorectal cancer,” Professor of Shu Chian-Jean Le Leago in UC San Diego and Professor of Cell-Sun Diego, Professor Lodmil Alakjand, Senior Authority.
“They may be decades before the schedule of colorectal cancer development.”
In the study, researchers have analyzed 981 colorectal cancer genome to patients with primary-looking and late-source colorectal cancer patients across 11 countries.
Those who had exposure prior to kolibactin seemed to have specific mutations in DNA, which originally found in the first decade of life – “As a young man, the advent of cancer as an adult.”

The exposure of bacteria toxin during childhood can change the DNA of colon cells in a way that increases the risk of colorectal cancer before the age of 50, survey. (Estock)
This group was 3.3 times more likely to develop primary-looking colorectal cancer than those who were diagnosed after 70.
These transformations have been shown to create 15% of primary genetic changes that increase the risk of colorectal cancer.
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Alexandrav noted, “We have identified the mutational signature of kolibactin in more than 50% of colorectal tumors from patients under 40% of the tumors from older people.”
Alexandrav mentions, “If someone earns a 10 year old of these driver mutations, they may be decades ago for the development of colorectal cancer, at the age of 40 instead of 60,” Alexandrav mentioned.
In the first few years of life, a microbial exposure can leave a “permanent genomic impression” and maybe it may contribute to cancer in youth both “extraordinary and comfortable” researchers.
He told Fox News Digital, “This is a reminder that we probably have many more exposure that we have not yet been able to reveal, and in these constructive years we can have long -term effects on their life health,” he told Fox News Digital.
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“From my point of view, investing in primary life resistance, healthy living and research is not only important-it is essential.”
Dr. Emil Lu, MD, PhD, Board-based oncologist and internal medicine physician at the University of Minnesota, agreed that microbiomes-“The constellations of the bacteria that live in our guts in our bowel”-this is a potential crime of Coretal Cancer.
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“It is now less surprising than a decade ago that any form of bacteria – especially, can be associated with a toxin obtained from bacteria, and may be the primary cause of cancer,” Lu, who was not involved in this study, told Fox News Digital.
“Particularly that is a long time that can fall into the early part of life, and in the previous period of cancer diagnosis.”
Potential restriction
Alexandrav noted that the study provided “strong genomic evidence” of a “striking association” between colorectal cancer, but could not prove effectiveness.
He told Fox News Digital, “Displaying incomplete effectiveness – prove that kolibactin alone is enough to start cancer in humans – it remains an important challenge,” he told Fox News Digital.

Statistics show that colorectal cancer cases have doubled in adults under the age of 50 for each of the last two decades. (Estock)
“For the specific evidence of effectiveness, the long -term possible study of the microbial colon colon penetrating and tracking the development of cancer is required for decades.”
Lu agrees with this constraint, notice the complications of the causes of cancer.
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“There are many aspects of our environment – both inside and outside our bodies – which can play a role in the development of cancer,” he said. “In this case a given single factor-in this case it is difficult to say whether or not to make this decision or to reach this decision whether toxin-chorectal cancer is a major cause of cancer.”
“Providing evidence of potential organizations to determine whether the true cause and effect is to determine the basis for a deeper study,” added.
“If the current trend continues, it is believed to be the main cause of cancer death among young adults by 2030.”
Alexandrav mentions that searchs still do not guarantee the change in screening or treatment guidelines, they highlight “the critical role of the microbial exposure of early life” in terms of long -term cancer risk.
He added, “We are actively working on screening tests to identify the long -term effects of kolibactin exposure, with the aim of translating these searches into practical resistance techniques in the near future,” he added.
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Statistics show that colorectal cancer cases have doubled in adults under the age of 50 for each of the last two decades.
“If the current trend continues, cancer cancer is believed to be the main cause of cancer cancer death by 2030,” researchers have concluded.